SCHEMBL7975426

SCHEMBL7975426

CCOC(=O)N1CCC(O)=C(C(C)=O)C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.41
MAPT P10636 4/20 0.41
KDM4E B2RXH2 3/20 0.41
TSHR P16473 1/20 0.41
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
PABPC1 P11940 1/20 0.40
ATM Q13315 1/20 0.40
ALDH1A1 P00352 3/20 0.40
POLB P06746 2/20 0.40
HTT P42858 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
RXFP1 Q9HBX9 3/20 0.39
ABL1 P00519 1/20 0.39
RIN1 Q13671 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
RECQL P46063 1/20 0.38
GRM5 P41594 2/20 0.38
CYP3A4 P08684 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7987480 0.83 MAPT (0.41) GAAMAPTKDM4ETSHRLMNA
SCHEMBL7985767 0.83 SMN1; SMN2 (0.42) GAAMAPTKDM4ETSHRLMNA
SCHEMBL7992154 0.82 MAPT (0.38) GAAMAPTKDM4ETSHRLMNA
SCHEMBL12764026 0.79 MEN1 (0.40) MAPTKDM4ETSHRSMN1; SMN2ALDH1A1
SCHEMBL18092279 0.79 MAPT (0.42) GAAMAPTKDM4ETSHRLMNA
SCHEMBL17611780 0.77 GAA (0.35) GAAMAPTKDM4ETSHRLMNA
SCHEMBL20998225 0.77 ADORA1 (0.55) GAAMAPTLMNASMN1; SMN2ATM
SCHEMBL4399188 0.75 TMEM97 (0.49) SMN1; SMN2L3MBTL1KMT2A
SCHEMBL17611778 0.75 ADORA1 (0.47) GAAMAPTKDM4ESMN1; SMN2GRM5
SCHEMBL568818 0.74 TSHR (0.47) GAAMAPTKDM4ETSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed