SCHEMBL568818

SCHEMBL568818

CCOC(=O)N1CCC(=O)C1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 4/20 0.46
MAPT P10636 4/20 0.46
GAA P10253 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
POLB P06746 2/20 0.46
HTT P42858 1/20 0.46
LMNA P02545 2/20 0.45
PABPC1 P11940 1/20 0.45
ATM Q13315 1/20 0.45
RXFP1 Q9HBX9 3/20 0.44
ABL1 P00519 1/20 0.44
RIN1 Q13671 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
RECQL P46063 1/20 0.43
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6306521 0.89 TSHR (0.44) TSHRALDH1A1KDM4EMAPTGAA
SCHEMBL158497 0.88 TSHR (0.55) TSHRALDH1A1KDM4EMAPTGAA
SCHEMBL28479793 0.87 CNR2 (0.44) TSHRALDH1A1KDM4EMAPTGAA
Hydrochloric Acid SCHEMBL27776511 0.86 TSHR (0.53) TSHRALDH1A1KDM4EMAPTGAA
SCHEMBL7380124 0.84 SMN1; SMN2 (0.54) TSHRALDH1A1KDM4EMAPTSMN1; SMN2
SCHEMBL8380828 0.84 ALDH1A1 (0.50) TSHRALDH1A1KDM4EMAPTGAA
SCHEMBL28484198 0.83 LMNA (0.49) TSHRSMN1; SMN2POLBLMNAMAPK1
SCHEMBL28486528 0.82 RAB9A (0.44) SMN1; SMN2LMNAPABPC1ATMTDP1
SCHEMBL28477466 0.82 LMNA (0.48) TSHRALDH1A1SMN1; SMN2POLBLMNA
SCHEMBL28484141 0.82 LMNA (0.48) TSHRALDH1A1SMN1; SMN2POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11158903-B2 Separators, articles and methods of making thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-10-26 US claimed
CN-109096415-B Olefin polymerization catalyst component, process for producing the same, olefin polymerization catalyst, and process for producing olefin polymer 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109096416-B Olefin polymerization catalyst component, process for producing the same, olefin polymerization catalyst, and process for producing olefin polymer 中国石油化工股份有限公司 2020-11-10 CN claimed
EP-3497735-A1 SEPARATORS, ARTICLES AND METHODS OF MAKING THEREOF SABIC Global Technologies B.V. (NL) 2019-06-19 EP claimed
US-20190181413-A1 SEPARATORS, ARTICLES and METHODS OF MAKING THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-06-13 US claimed
CN-109565015-A Diaphragm, product and its manufacturing method 沙特基础工业全球技术有限公司 2019-04-02 CN claimed
EP-2880701-A1 HIGH TEMPERATURE MELT INTEGRITY SEPARATOR SABIC Global Technologies B.V. (NL) 2015-06-10 EP claimed
WO-2014020545-A1 HIGH TEMPERATURE MELT INTEGRITY SEPARATOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-02-06 WO claimed
US-20140030608-A1 HIGH TEMPERATURE MELT INTEGRITY SEPARATOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-30 US claimed
CN-110407730-B Pyrrolidone herbicides FMC 公司 2023-09-08 CN disclosed
US-11158903-B2 Separators, articles and methods of making thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-10-26 US disclosed
CN-109096415-B Olefin polymerization catalyst component, process for producing the same, olefin polymerization catalyst, and process for producing olefin polymer 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-105753768-B Production method of single nitrogen heterocyclic compound 北京恒瑞新霖科技有限公司 2020-11-27 CN disclosed
CN-109096416-B Olefin polymerization catalyst component, process for producing the same, olefin polymerization catalyst, and process for producing olefin polymer 中国石油化工股份有限公司 2020-11-10 CN disclosed
EP-0156433-A2 Anti-virally active pyridazinamines JANSSEN PHARMACEUTICA N.V. (BE) 1985-10-02 EP disclosed
EP-0111864-A1 1,4-Benzodiazepine derivatives SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1984-06-27 EP disclosed
US-4299768-A 1-Pyrrole- and 1-pyrrolidine-carboxylic acid derivatives and process for preparing the same LABAZ (FR) 1981-11-10 US disclosed
US-4014890-A REACTING A PHENYLHYDRAZINE SALT AND A KETONE IN A WEAK BASE PFIZER INC. (US) 1977-03-29 US disclosed
US-4006164-A TRANQUILIZER PFIZER INC. (US) 1977-02-01 US disclosed
US-3968231-A 4-Aryl-1,2,3,4-tetrahydropyrrolo(3,4-b)indoles for treating schizophrenic manifestations BAYER AKTIENGESELLSCHAFT (DT) 1976-07-06 US disclosed