Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992501 | 0.84 | TSHR (0.41) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7975426 | 0.83 | GAA (0.41) | MAPTLMNASMN1; SMN2KMT2APABPC1 | |
| SCHEMBL7992154 | 0.78 | MAPT (0.38) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20998225 | 0.76 | ADORA1 (0.55) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8138202 | 0.75 | CHRM2 (0.32) | HRH2HRH1 | |
| SCHEMBL18092279 | 0.75 | MAPT (0.42) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL17611778 | 0.74 | ADORA1 (0.47) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL12764026 | 0.73 | MEN1 (0.40) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL4399188 | 0.71 | TMEM97 (0.49) | SMN1; SMN2MEN1KMT2AHRH2HRH1 | |
| SCHEMBL568818 | 0.71 | TSHR (0.47) | MAPTLMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |