Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974849 | 0.92 | SMN1; SMN2 (0.35) | RAB9ASMN1; SMN2NPC1HPGDL3MBTL1 | |
| SCHEMBL7990319 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1HPGDMAPK1ALDH1A1 | |
| SCHEMBL7986794 | 0.83 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL7985659 | 0.80 | RAB9A (0.45) | RAB9ASMN1; SMN2NPC1HPGDL3MBTL1 | |
| SCHEMBL130033 | 0.80 | TSHR (0.49) | RAB9ASMN1; SMN2HPGDL3MBTL1MAPK1 | |
| SCHEMBL7989755 | 0.79 | — | — | |
| SCHEMBL7975327 | 0.78 | LMNA (0.44) | RAB9ASMN1; SMN2NPC1L3MBTL1MAPT | |
| SCHEMBL7992455 | 0.76 | NPC1 (0.44) | RAB9ASMN1; SMN2NPC1HPGDL3MBTL1 | |
| SCHEMBL7985754 | 0.75 | EPHX1 (0.46) | RAB9ASMN1; SMN2NPC1HPGDL3MBTL1 | |
| SCHEMBL7988847 | 0.75 | RAB9A (0.43) | RAB9ASMN1; SMN2NPC1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |