Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21819899 | 0.86 | ESR1 (0.53) | ESR1ESR2CHEK1FYNPDGFRB | |
| SCHEMBL7972783 | 0.86 | CHEK1 (0.42) | ESR1ESR2CYP3A4ALDH1A1CACNA1B | |
| SCHEMBL7969173 | 0.82 | ESR1 (0.61) | ESR1ESR2CYP3A4ALDH1A1CACNA1B | |
| SCHEMBL730689 | 0.81 | ESR1 (0.67) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL7946326 | 0.80 | HSD17B10 (0.43) | ESR1ESR2CYP3A4ALDH1A1CHEK1 | |
| SCHEMBL5078080 | 0.80 | ESR1 (0.46) | ESR1ESR2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL30713707 | 0.80 | ESR1 (0.61) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL10865833 | 0.80 | ESR1 (0.61) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL8915558 | 0.80 | ESR1 (0.37) | ESR1ESR2CYP3A4ALDH1A1CACNA1B | |
| SCHEMBL7594834 | 0.79 | CHEK1 (0.68) | ESR1ESR2CYP3A4ALDH1A1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268462-B1 | Branched polycarbonate resin and process for the preparation thereof | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-1008608-A1 | BRANCHED POLYCARBONATE RESIN AND PROCESS FOR THE PREPARATION THEREOF | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-4415725-A | MOLDING MATERIALS; BLOW MOLDING; BOTTLES; FILMS | GENERAL ELECTRIC CO. (US) | 1983-11-15 | — | — | US | disclosed |