Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078080 | 0.85 | ESR1 (0.46) | HSD17B10TSHRKLF10CA2CA1 | |
| SCHEMBL7975485 | 0.80 | ESR1 (0.49) | HSD17B10TSHRCA2CA1ALDH1A1 | |
| SCHEMBL7972783 | 0.80 | CHEK1 (0.42) | HSD17B10TSHRKLF10CA2CA1 | |
| SCHEMBL21819899 | 0.80 | ESR1 (0.53) | CA2CA1ESR1CHEK1FYN | |
| SCHEMBL21221690 | 0.80 | RORC (0.40) | HSD17B10TSHRKLF10CA2CA1 | |
| SCHEMBL7510606 | 0.80 | ESR1 (0.63) | HSD17B10KLF10ALDH1A1HPGDALOX15 | |
| SCHEMBL4465664 | 0.79 | ESR1 (0.52) | HSD17B10TSHRKLF10CA2CA1 | |
| SCHEMBL37041 | 0.79 | ESR1 (0.61) | HSD17B10TSHRKLF10CA2CA1 | |
| SCHEMBL29479453 | 0.79 | ESR1 (0.61) | HSD17B10TSHRKLF10CA2CA1 | |
| SCHEMBL29465799 | 0.79 | ESR1 (0.52) | HSD17B10TSHRKLF10CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258498-B1 | POLYCARBONATE PROTECTIVE COATING | CANON KABUSHIKI KAISHA (JP) | 2001-07-10 | — | — | US | disclosed |