SCHEMBL7972783

SCHEMBL7972783

CC(CCC(C)(c1ccc(O)c(Cl)c1)c1cc(Cl)c(O)c(Cl)c1)(c1ccc(O)c(Cl)c1)c1ccc(O)c(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.42
FYN P06241 1/20 0.42
PDGFRB P09619 1/20 0.42
PIM1 P11309 1/20 0.42
FGFR1 P11362 1/20 0.42
FLT1 P17948 1/20 0.42
GRK5 P34947 1/20 0.42
MAP2K2 P36507 1/20 0.42
MAPK8 P45983 1/20 0.42
CDK8 P49336 1/20 0.42
RPS6KA3 P51812 1/20 0.42
PRKX P51817 1/20 0.42
JAK3 P52333 1/20 0.42
LIMK1 P53667 1/20 0.42
BTK Q06187 1/20 0.42
TYRO3 Q06418 1/20 0.42
MAPK14 Q16539 1/20 0.42
TAOK1 Q7L7X3 1/20 0.42
CAMK1D Q8IU85 1/20 0.42
AURKB Q96GD4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11781384 0.88 HSD17B10 (0.38) CHEK1FYNPDGFRBPIM1FGFR1
SCHEMBL671782 0.87 ALOX15 (0.51) CHEK1FYNPDGFRBPIM1FGFR1
SCHEMBL7975485 0.86 ESR1 (0.49) CHEK1FYNPDGFRBPIM1FGFR1
SCHEMBL21819899 0.86 ESR1 (0.53) CHEK1FYNPDGFRBPIM1FGFR1
SCHEMBL7972195 0.82 CHEK1 (0.37) CHEK1FYNPDGFRBPIM1FGFR1
SCHEMBL7946326 0.80 HSD17B10 (0.43) CHEK1FYNPDGFRBPIM1FGFR1
SCHEMBL9716020 0.80 ESR1 (0.53) HSD17B10TSHRCA2CA1CYP2C9
SCHEMBL5078080 0.80 ESR1 (0.46) HSD17B10TSHRCA2CA1ALDH1A1
SCHEMBL7594834 0.79 CHEK1 (0.68) CHEK1FYNPDGFRBPIM1FGFR1
SCHEMBL11566874 0.78 ESR1 (0.41) HSD17B10TSHRCYP2C9CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268462-B1 Branched polycarbonate resin and process for the preparation thereof IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-07-31 US disclosed
EP-1008608-A1 BRANCHED POLYCARBONATE RESIN AND PROCESS FOR THE PREPARATION THEREOF IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-06-14 EP disclosed
US-4415725-A MOLDING MATERIALS; BLOW MOLDING; BOTTLES; FILMS GENERAL ELECTRIC CO. (US) 1983-11-15 US disclosed