Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507530 | 0.85 | HTT (0.39) | HTTALDH1A1MEN1POLBHPGD | |
| SCHEMBL7456495 | 0.81 | HTT (0.36) | HTTALDH1A1MEN1POLBHPGD | |
| SCHEMBL7989177 | 0.80 | HTT (0.43) | HTT | |
| SCHEMBL7451964 | 0.80 | HTT (0.48) | HTTMEN1POLBKMT2A | |
| SCHEMBL7990277 | 0.79 | HTT (0.43) | HTTMEN1HPGDKMT2A | |
| SCHEMBL7451566 | 0.78 | HTT (0.58) | HTTPOLBKMT2A | |
| SCHEMBL7508403 | 0.78 | HTT (0.42) | HTTMEN1KMT2A | |
| SCHEMBL7987189 | 0.77 | IDO1 (0.41) | HTTALDH1A1MEN1POLBHPGD | |
| SCHEMBL7508484 | 0.76 | HTT (0.40) | HTTALDH1A1MEN1POLBHPGD | |
| SCHEMBL7986938 | 0.76 | HTT (0.43) | HTTALDH1A1MEN1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |