Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.39 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 9/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990277 | 0.84 | HTT (0.43) | HTTIDO1AGXTMAOB | |
| SCHEMBL7451566 | 0.84 | HTT (0.58) | HTT | |
| SCHEMBL7975492 | 0.80 | HTT (0.37) | HTT | |
| SCHEMBL7987189 | 0.80 | IDO1 (0.41) | HTTIDO1AGXTTDP1MAOB | |
| SCHEMBL7451964 | 0.79 | HTT (0.48) | HTTIDO1KDM4ETDP1 | |
| SCHEMBL7450571 | 0.79 | HTT (0.53) | HTT | |
| SCHEMBL7986938 | 0.79 | HTT (0.43) | HTT | |
| SCHEMBL7510301 | 0.79 | HTT (0.32) | HTTKDM4ETDP1 | |
| SCHEMBL7507063 | 0.78 | HTT (0.45) | HTT | |
| SCHEMBL7989793 | 0.77 | HTT (0.44) | HTTAGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |