Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510301 | 0.86 | HTT (0.32) | SLC6A2SLC6A4HTTALDH1A1MEN1 | |
| SCHEMBL7507530 | 0.84 | HTT (0.39) | IDO1MAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7990277 | 0.81 | HTT (0.43) | IDO1AGXTMAOBHTTMEN1 | |
| SCHEMBL7456495 | 0.80 | HTT (0.36) | IDO1MAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7989177 | 0.80 | HTT (0.43) | IDO1AGXTMAOBHTTTDP1 | |
| SCHEMBL7451964 | 0.79 | HTT (0.48) | IDO1HTTMEN1POLBKMT2A | |
| SCHEMBL7975492 | 0.77 | HTT (0.37) | HTTMMP1ALDH1A1MEN1POLB | |
| SCHEMBL7988725 | 0.77 | HTT (0.35) | SLC6A4HTTALDH1A1 | |
| SCHEMBL7508484 | 0.76 | HTT (0.40) | MAOBSLC6A2SLC6A4SLC6A3GRIN2B | |
| SCHEMBL7992894 | 0.74 | HTT (0.41) | IDO1HTTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |