Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479034 | 0.90 | ATM (0.54) | ATMPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6479030 | 0.90 | ATM (0.54) | ATMPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6121239 | 0.90 | ATM (0.54) | ATMPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6120583 | 0.82 | ATM (0.48) | ATMPOLBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL19665873 | 0.79 | ATM (0.49) | ATMPOLBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL18260473 | 0.79 | ATM (0.49) | ATMPOLBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL31724344 | 0.79 | ATM (0.49) | ATMPOLBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL30771269 | 0.79 | ATM (0.49) | ATMPOLBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL30771314 | 0.79 | ATM (0.49) | ATMPOLBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL8286085 | 0.76 | ROCK2 (0.52) | POLBALDH1A1MTNR1AMTNR1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303611-B1 | FOR THERAPY OF HYPERALGESIS | ADOLOR CORPORATION | 2001-10-16 | — | — | US | disclosed |