Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1582559 | 0.86 | TSHR (0.46) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL1022578 | 0.86 | TSHR (0.46) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL1583098 | 0.86 | TSHR (0.46) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL29210391 | 0.85 | MEN1 (0.42) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL28368681 | 0.84 | SLC18A3 (0.45) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL28373802 | 0.84 | SLC18A3 (0.45) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL28368682 | 0.84 | SLC18A3 (0.45) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL2962446 | 0.81 | LMNA (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2MEN1 | |
| Methyl Alcohol SCHEMBL8766472 | 0.81 | EPHX1 (0.49) | ALDH1A1LMNAMEN1KMT2ARECQL | |
| SCHEMBL28351479 | 0.80 | HTT (0.39) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | disclosed |