Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 7/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 7/20 | 0.46 |
| ▸ | MGAM | O43451 | 6/20 | 0.46 |
| ▸ | SI | P14410 | 6/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816937 | 0.85 | CYP1A2 (0.59) | CYP1A2CYP2D6GRIN2BDHODHPARP1 | |
| SCHEMBL6687964 | 0.78 | GRIN2B (0.60) | CYP1A2CYP2D6GRIN2BDHODHPARP1 | |
| SCHEMBL3969183 | 0.78 | GRIN2B (0.60) | CYP1A2CYP2D6GRIN2BDHODHPARP1 | |
| SCHEMBL6686102 | 0.77 | MGAM (0.62) | CYP1A2CYP2D6GRIN2BDHODHPARP1 | |
| SCHEMBL7210788 | 0.75 | GRIN2B (0.58) | CYP1A2CYP2D6GRIN2BDHODHPARP1 | |
| SCHEMBL7211155 | 0.75 | GRIN2B (0.58) | CYP1A2CYP2D6GRIN2BDHODHPARP1 | |
| SCHEMBL30615069 | 0.72 | MGAM (0.76) | PARP1GAAMGAMSIMGAM2 | |
| SCHEMBL5074029 | 0.72 | MGAM (0.76) | PARP1GAAMGAMSIMGAM2 | |
| SCHEMBL8814837 | 0.72 | GRIN2B (0.54) | CYP1A2CYP2D6GRIN2BDHODHPARP1 | |
| SCHEMBL7461763 | 0.72 | GRIN2B (0.54) | CYP1A2CYP2D6GRIN2BDHODHPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194396-B1 | ANTIALLERGENS; ANTIINFLAMMATION AGENTS; AUTOIMMUNE DISEASE; ANTISHOCK AGENTS; ANALGESICS; E.G., A 4 OR 7-PHENYLALKYLENE-OXYBENZIMIDAZOLE UNSUBSTITUTED OR SUBSTITUTED IN THE 1,2,3-POSITION WITH AN OXY, AMINO AND/OR THIO GROUP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |