Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965986 | 0.97 | PTGES (0.34) | PTGESAVPR2AVPR1AAVPR1BLCK | |
| Hydrochloric Acid SCHEMBL7967145 | 0.97 | PTGES (0.34) | PTGESAVPR2AVPR1AAVPR1BLCK | |
| SCHEMBL7978293 | 0.95 | AVPR2 (0.34) | PTGESAVPR2AVPR1AAVPR1BLCK | |
| SCHEMBL7967127 | 0.94 | AVPR2 (0.34) | PTGESAVPR2AVPR1AAVPR1BLCK | |
| Hydrochloric Acid SCHEMBL7963628 | 0.94 | AVPR2 (0.34) | PTGESAVPR2AVPR1AAVPR1BLCK | |
| Hydrochloric Acid SCHEMBL7978209 | 0.94 | AVPR2 (0.33) | PTGESAVPR2AVPR1AAVPR1BLCK | |
| SCHEMBL7975620 | 0.94 | AVPR2 (0.34) | AVPR2AVPR1AAVPR1BLCKMAPT | |
| Hydrochloric Acid SCHEMBL7953946 | 0.93 | AVPR2 (0.34) | AVPR2AVPR1AAVPR1BLCKMAPT | |
| SCHEMBL7480849 | 0.91 | AVPR2 (0.35) | AVPR2AVPR1AAVPR1BMAP3K7PDE3B | |
| SCHEMBL7483272 | 0.91 | AVPR2 (0.37) | PTGESAVPR2AVPR1AAVPR1BMAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |