Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127600 | 0.87 | HSD17B10 (0.50) | MEN1KMT2APOLBGLAHSD17B10 | |
| SCHEMBL255933 | 0.84 | DDB1 (0.43) | MEN1KMT2ASETD7SMN1; SMN2ESR2 | |
| SCHEMBL20564793 | 0.84 | DDB1 (0.43) | MEN1KMT2ASETD7SMN1; SMN2ESR2 | |
| SCHEMBL18897507 | 0.84 | DDB1 (0.43) | MEN1KMT2ASETD7SMN1; SMN2ESR2 | |
| SCHEMBL1256025 | 0.78 | KMT2A (0.92) | MEN1KMT2ASTSHTTSMN1; SMN2 | |
| SCHEMBL1963747 | 0.77 | HPGD (0.44) | MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL3985720 | 0.76 | KMT2A (0.56) | MEN1KMT2ASTSHTTSMN1; SMN2 | |
| SCHEMBL3068899 | 0.74 | KMT2A (1.00) | MEN1KMT2ASTSHTTSMN1; SMN2 | |
| SCHEMBL1965378 | 0.73 | MAPT (0.49) | HTTSMN1; SMN2MAPT | |
| SCHEMBL17711779 | 0.72 | KMT2A (0.61) | MEN1KMT2ASTSHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001058867-A2 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | WO | disclosed |