Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975740 | 0.87 | MEN1 (0.59) | HSD17B10GLAMGLLMAPTPOLB | |
| SCHEMBL7116692 | 0.82 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL11068661 | 0.76 | ALDH1A1 (0.64) | HSD17B10MGLLALDH1A1HPGDMAPT | |
| SCHEMBL1799068 | 0.76 | ALDH1A1 (0.64) | HSD17B10MGLLALDH1A1HPGDMAPT | |
| SCHEMBL10732800 | 0.74 | MGLL (0.49) | HSD17B10GLAMGLLALDH1A1MAPT | |
| SCHEMBL447927 | 0.74 | HPGD (0.47) | HSD17B10GLAMGLLALDH1A1HPGD | |
| SCHEMBL14275540 | 0.74 | HSD17B10 (0.61) | HSD17B10GLAMGLLALDH1A1HPGD | |
| SCHEMBL4223562 | 0.74 | HSD17B10 (0.61) | HSD17B10GLAMGLLALDH1A1HPGD | |
| Ethylene SCHEMBL8379754 | 0.73 | ALDH1A1 (0.60) | HSD17B10MGLLALDH1A1HPGDMAPT | |
| SCHEMBL9585721 | 0.73 | POLB (0.81) | HSD17B10MGLLALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064978-A1 | Novel compounds | ASTRAZENECA AB. (SE) | 2003-04-03 | — | — | US | disclosed |
| WO-2001058867-A2 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064978-A1 | Novel compounds | NOS1, NOS3, NOS2 | HSD17B10 301/4885GLA 2091/4885MGLL 3511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.