SCHEMBL255933

SCHEMBL255933

CC(C)(C)OC(=O)N1CCC(=O)C(F)C1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 2/20 0.43
CRBN Q96SW2 2/20 0.43
USP2 O75604 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ESR2 Q92731 1/20 0.42
NR1H2 P55055 2/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 2/20 0.41
THRB P10828 1/20 0.41
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
KMT2A Q03164 1/20 0.40
SETD7 Q8WTS6 1/20 0.39
GPR119 Q8TDV5 1/20 0.39
ADORA1 P30542 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18897507 1.00 DDB1 (0.43) DDB1CRBNUSP2SMN1; SMN2ESR2
SCHEMBL20564793 1.00 DDB1 (0.43) DDB1CRBNUSP2SMN1; SMN2ESR2
SCHEMBL1963747 0.91 HPGD (0.44) DDB1CRBNUSP2SMN1; SMN2NR1H2
SCHEMBL1965378 0.86 MAPT (0.49) DDB1CRBNUSP2SMN1; SMN2MAPT
SCHEMBL7975740 0.84 MEN1 (0.59) SMN1; SMN2ESR2MAPTMEN1KMT2A
SCHEMBL954970 0.84 NR1H2 (0.43) DDB1CRBNUSP2SMN1; SMN2ESR2
SCHEMBL15227433 0.83 USP2 (0.41) DDB1CRBNUSP2SMN1; SMN2ESR2
SCHEMBL104498 0.83 USP2 (0.44) DDB1CRBNUSP2SMN1; SMN2ESR2
SCHEMBL12908934 0.83 USP2 (0.44) DDB1CRBNUSP2SMN1; SMN2ESR2
SCHEMBL21241481 0.83 USP2 (0.44) DDB1CRBNUSP2SMN1; SMN2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 840 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115385849-B Method for purifying N-Boc-3-fluoro-4-piperidone 南通瑞合达医药科技有限公司 2024-01-26 CN claimed
CN-115385849-A Method for purifying N-Boc-3-fluoro-4-piperidone 南通瑞合达医药科技有限公司 2022-11-25 CN claimed
CN-114853768-A Method for synthesizing chiral 3-fluoro-1-azabicyclo [2,2,1] heptane 南昌大学 2022-08-05 CN claimed
US-20260116888-A1 CYCLIN-DEPENDENT KINASE INHIBITORS NOVARTIS AG (CH) 2026-04-30 US disclosed
US-20260098049-A1 KRAS MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2026-04-09 US disclosed
US-20260098032-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION PMV PHARMACEUTICALS INC (US) 2026-04-09 US disclosed
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
US-20260070917-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF DIFFERENTIATED THERAPEUTICS INC (US) 2026-03-12 US disclosed
US-20260070902-A1 SULFONYL DERIVATIVES AS CCR6 INHIBITORS HOFFMANN-LA ROCHE INC. (US) 2026-03-12 US disclosed
US-20260042782-A1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR C4 THERAPEUTICS, INC. (US) 2026-02-12 US disclosed
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP disclosed
US-20030078249-A1 VLA-4 inhibitor compounds DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-04-24 US disclosed
US-20030064978-A1 Novel compounds ASTRAZENECA AB. (SE) 2003-04-03 US disclosed
CN-1391473-A VLA-4 inhibitor compounds DAIICHI SEIYAKU CO (JP) 2003-01-15 CN disclosed
US-6495565-B2 FOR THERAPY OF ACUTE INFECTION, ACUTE PHASE RESPONSE, AGE RELATED MACULAR DEGENERATION, ALCOHOLISM, ANOREXIA, ASTHMA, AUTOIMMUNE DISEASE, AUTOIMMUNE HEPATITIS, BECHET'S DISEASE, CACHEXIA, CALCIUM PYROPHOSPHATE DIHYDRTATE DEPOSITION BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-12-17 US disclosed
US-20020165227-A1 Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment WOCKHARDT RESEARCH CENTER 2002-11-07 US disclosed
EP-1189612-A1 VLA-4 INHIBITOR COMPOUNDS Daiichi Pharmaceutical Co., Ltd. (JP) 2002-03-27 EP disclosed
US-20020013341-A1 Beta-Amino-Acid derivatives as inhibitors of matrix metalloproteases and TNF-Alpha BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-01-31 US disclosed
WO-2001000206-A1 VLA-4 INHIBITOR COMPOUNDS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-01-04 WO disclosed
US-5837715-A 3-fluoro-4-aminopiperidine derivatives as 5-HT receptor agonists MERCK SHARP & DOHME LTD. (GB) 1998-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030078249-A1 VLA-4 inhibitor compounds VCAM1, ICAM1, ITGA4 DDB1 3788/4885CRBN 3806/4885USP2 4855/4885
US-20260116888-A1 CYCLIN-DEPENDENT KINASE INHIBITORS CDK4, CCNC, CDK6 DDB1 209/4885CRBN 83/4885USP2 2411/4885
US-20030064978-A1 Novel compounds NOS1, NOS3, NOS2 DDB1 4191/4885CRBN 2656/4885USP2 1260/4885
US-20260070902-A1 SULFONYL DERIVATIVES AS CCR6 INHIBITORS CCR6, CCR1, CCR4 DDB1 1408/4885CRBN 363/4885USP2 2569/4885
US-20260098049-A1 KRAS MODULATING COMPOUNDS KRAS, NRAS, HRAS DDB1 992/4885CRBN 179/4885USP2 1404/4885
US-20260098032-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION TP53, TP53BP1, MDM2 DDB1 79/4885CRBN 1490/4885USP2 1735/4885
US-20260042782-A1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR EGFR, ERBB2, ERBB3 DDB1 823/4885CRBN 25/4885USP2 63/4885
US-20020165227-A1 Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment ALPI, POLR1C, POLI DDB1 2195/4885CRBN 3894/4885USP2 3755/4885
US-20020013341-A1 Beta-Amino-Acid derivatives as inhibitors of matrix metalloproteases and TNF-Alpha TNF, XPNPEP1, MMP2 DDB1 3723/4885CRBN 4454/4885USP2 736/4885
US-20260070917-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF CDK2, CCNK, CCNC DDB1 270/4885CRBN 277/4885USP2 519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.