Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31635870 | 0.81 | EGFR (0.55) | EGFRALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL28350331 | 0.77 | EGFR (0.62) | EGFRALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL9321547 | 0.77 | EGFR (0.62) | EGFRALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL9321542 | 0.77 | EGFR (0.62) | EGFRALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL9480701 | 0.76 | ALDH1A1 (0.52) | EGFRALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL28852837 | 0.76 | ALDH1A1 (0.52) | EGFRALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL49338 | 0.72 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EHDAC1HDAC2 | |
| SCHEMBL6233317 | 0.72 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EHDAC1HDAC2 | |
| SCHEMBL49339 | 0.72 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EHDAC1HDAC2 | |
| SCHEMBL23209621 | 0.71 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009124-A1 | 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPIC USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |