Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23971349 | 1.00 | KLK5 (0.52) | KLK5KLK7SYKCTSKPPARA | |
| SCHEMBL1261930 | 1.00 | KLK5 (0.52) | KLK5KLK7SYKCTSKPPARA | |
| SCHEMBL2062558 | 0.90 | SYK (0.55) | SYKCTSKATMCTSBCTSL | |
| SCHEMBL187066 | 0.90 | SYK (0.55) | SYKCTSKATMCTSBCTSL | |
| SCHEMBL2061787 | 0.90 | SYK (0.55) | SYKCTSKATMCTSBCTSL | |
| SCHEMBL25491975 | 0.87 | CTSB (0.51) | CTSKCTSBCTSL | |
| SCHEMBL29458828 | 0.84 | SYK (0.63) | SYKCTSKPPARAATMCTSB | |
| SCHEMBL8311926 | 0.84 | CTSK (0.56) | SYKCTSKCTSBCTSLMAPT | |
| SCHEMBL28807325 | 0.84 | SYK (0.41) | KLK5KLK7SYKCTSKPPARA | |
| SCHEMBL75663 | 0.84 | KLK5 (0.55) | KLK5KLK7SYKCTSKPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117820333-A | KRAS G12C inhibitors | 伊莱利利公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-114828964-B | KRAS G12C inhibitors | 伊莱利利公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-112135830-A | Oxo substituted compounds | 大日本住友制药株式会社 | 2020-12-25 | — | — | CN | disclosed |
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |