Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5725294 | 0.81 | PTGER2 (0.44) | LMNAHDAC6 | |
| SCHEMBL5726033 | 0.80 | PTGER2 (0.43) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL5726191 | 0.76 | CNR2 (0.39) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL5724841 | 0.76 | PTGER2 (0.39) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL5724807 | 0.76 | CNR2 (0.42) | ALDH1A1KDM4EHPGD | |
| SCHEMBL5725428 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL5725381 | 0.74 | HPGD (0.39) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL7975936 | 0.74 | POLB (0.36) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL5726433 | 0.74 | SLC6A4 (0.49) | ALDH1A1 | |
| SCHEMBL5725804 | 0.72 | KMT2A (0.41) | ALDH1A1LMNAPRNPRECQLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288120-B1 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. | 2001-09-11 | — | — | US | disclosed |