Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726033 | 0.76 | PTGER2 (0.43) | POLBPTGER4ALDH1A1LMNAPRNP | |
| SCHEMBL7975931 | 0.74 | ALDH1A1 (0.35) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL5725294 | 0.72 | PTGER2 (0.44) | LMNAHDAC6PTGER2PTGER3PTGDR | |
| SCHEMBL5725428 | 0.70 | ALDH1A1 (0.43) | POLBTDP1PTGER4ALDH1A1LMNA | |
| SCHEMBL5725381 | 0.70 | HPGD (0.39) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL5725734 | 0.69 | KDM4E (0.49) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5726191 | 0.68 | CNR2 (0.39) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL5726433 | 0.67 | SLC6A4 (0.49) | ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL5724841 | 0.67 | PTGER2 (0.39) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL2769588 | 0.67 | TAS2R14 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307061-B2 | USEFUL AS AN ANALGESIC, ANESTHETIC, ANTI-INFLAMMATORY OR NEUROPROTECIVE AGENT | PFIZER INC. | 2001-10-23 | — | — | US | disclosed |
| US-6288120-B1 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. | 2001-09-11 | — | — | US | disclosed |