SCHEMBL7975933

SCHEMBL7975933

C=C(C)OC(=O)NC(=N)c1cc[c]c(OC)c1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7985588 0.84
SCHEMBL7986786 0.83
SCHEMBL7988714 0.81 KDM4E (0.40)
SCHEMBL7985973 0.79 HSD17B10 (0.31)
SCHEMBL7989518 0.79 CYP1A2 (0.41) S1PR3
SCHEMBL7985387 0.75
SCHEMBL7975771 0.74 CA1 (0.30)
SCHEMBL7988238 0.74 TSHR (0.36) S1PR3
SCHEMBL221066 0.72 ALDH1A1 (0.42)
SCHEMBL3964444 0.71 CA1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6288120-B1 Prevention of loss and restoration of bone mass by certain prostaglandin agonists PFIZER INC. 2001-09-11 US disclosed
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed