SCHEMBL7989518

SCHEMBL7989518

COc1[c]ccc(C(=N)NC(=O)Oc2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.41
S1PR3 Q99500 2/20 0.41
ALDH1A1 P00352 5/20 0.39
GAA P10253 5/20 0.39
HTT P42858 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 2/20 0.38
HPGD P15428 2/20 0.38
GLA P06280 1/20 0.38
ATM Q13315 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 2/20 0.36
MAPT P10636 2/20 0.36
PPARG P37231 1/20 0.36
NCOA2 Q15596 1/20 0.36
NCOA1 Q15788 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7986303 0.85 CYP1A2 (0.43) CYP1A2S1PR3ALDH1A1GAAHTT
SCHEMBL7989503 0.82 CYP1A2 (0.40) CYP1A2S1PR3ALDH1A1GAAKDM4E
SCHEMBL7988238 0.80 TSHR (0.36) CYP1A2S1PR3ALDH1A1GAASMN1; SMN2
SCHEMBL7988714 0.80 KDM4E (0.40) CYP1A2ALDH1A1GAAHTTSMN1; SMN2
SCHEMBL7975933 0.79 S1PR3 (0.30) S1PR3
SCHEMBL7988545 0.78 SLC1A3 (0.41) CYP1A2S1PR3ALDH1A1GAAHTT
SCHEMBL7985387 0.74
SCHEMBL7975771 0.73 CA1 (0.30)
SCHEMBL7988304 0.73 SMN1; SMN2 (0.44) CYP1A2S1PR3ALDH1A1GAAHTT
SCHEMBL7992609 0.73 CCNE1 (0.37) CYP1A2S1PR3ALDH1A1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed