Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726138 | 0.87 | GRM5 (0.42) | MRGPRX4TP53ALDH1A1HPGDPTGER2 | |
| SCHEMBL7975973 | 0.84 | MRGPRX4 (0.35) | MRGPRX4TP53ALDH1A1HPGDMAPT | |
| SCHEMBL5727377 | 0.77 | TAAR1 (0.39) | MRGPRX4ALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL5725353 | 0.73 | MRGPRX4 (0.40) | MRGPRX4ALDH1A1HPGD | |
| SCHEMBL5725361 | 0.73 | PLAAT3 (0.39) | MRGPRX4ALDH1A1HPGDMAPTPOLB | |
| SCHEMBL5726264 | 0.72 | SLC2A1 (0.43) | MRGPRX4ALDH1A1HPGDLMNAPRNP | |
| SCHEMBL5048133 | 0.72 | MRGPRX4 (0.39) | MRGPRX4ALDH1A1MAPTPTGER2 | |
| SCHEMBL5725437 | 0.70 | MRGPRX4 (0.44) | MRGPRX4HPGDMAPTLMNA | |
| SCHEMBL5046569 | 0.70 | CNR1 (0.47) | MRGPRX4TP53ALDH1A1MAPTLMNA | |
| SCHEMBL5726033 | 0.69 | PTGER2 (0.43) | ALDH1A1LMNAPRNPRECQLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288120-B1 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. | 2001-09-11 | — | — | US | disclosed |