Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.33 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.33 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.33 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975976 | 0.84 | MRGPRX4 (0.40) | MRGPRX4HPGDLMNAALDH1A1PRNP | |
| SCHEMBL5726138 | 0.82 | GRM5 (0.42) | MRGPRX4HPGDTAAR1ALDH1A1PTGER2 | |
| SCHEMBL5727377 | 0.72 | TAAR1 (0.39) | MRGPRX4HPGDTAAR1ALDH1A1PLAAT3 | |
| SCHEMBL7975971 | 0.72 | CYP2D6 (0.37) | HPGDALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL5725353 | 0.69 | MRGPRX4 (0.40) | MRGPRX4HPGDTAAR1ALDH1A1PLAAT3 | |
| SCHEMBL5725361 | 0.69 | PLAAT3 (0.39) | MRGPRX4HPGDTAAR1ALDH1A1MAPT | |
| SCHEMBL5726264 | 0.68 | SLC2A1 (0.43) | MRGPRX4HPGDTAAR1LMNAALDH1A1 | |
| SCHEMBL5048133 | 0.67 | MRGPRX4 (0.39) | MRGPRX4TAAR1ALDH1A1PTGER2PTGER4 | |
| SCHEMBL5726033 | 0.67 | PTGER2 (0.43) | LMNAALDH1A1PRNPRECQLRXFP1 | |
| SCHEMBL5725437 | 0.66 | MRGPRX4 (0.44) | MRGPRX4HPGDTAAR1LMNAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288120-B1 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. | 2001-09-11 | — | — | US | disclosed |