Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.54 |
| ▸ | LDHB | P07195 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797087 | 0.98 | LDHA (0.56) | LDHALDHBPTPN1PTPN11PTPN2 | |
| SCHEMBL797610 | 0.87 | LDHA (0.50) | LDHALDHBPTPN1PTPN11JUN | |
| SCHEMBL797416 | 0.87 | LDHA (0.49) | LDHALDHBPTPN1PTPN11KDM4E | |
| SCHEMBL1444836 | 0.84 | LDHA (0.51) | LDHALDHBPTPN1PTPN11PTPN2 | |
| SCHEMBL797384 | 0.84 | LDHA (0.44) | LDHALDHBPTPN1PTPN11PTPN2 | |
| SCHEMBL797104 | 0.81 | LDHA (0.47) | LDHALDHBPTPN1PTPN11PTPN2 | |
| SCHEMBL797383 | 0.80 | KMT2A (0.43) | LDHALDHBPPARGHPGD | |
| SCHEMBL14989214 | 0.79 | LDHA (0.46) | LDHALDHBPTPN1PTPN11PTPN2 | |
| SCHEMBL22418967 | 0.79 | LDHA (0.48) | LDHALDHBPTPN1PTPN11PTPN2 | |
| SCHEMBL797755 | 0.78 | KDM4E (0.50) | LDHALDHBJUNKDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1262469-B1 | POLYACENE DERIVATIVES AND PRODUCTION THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-7901594-B2 | Electroconductivity | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2011-03-08 | — | — | US | disclosed |
| US-20030116755-A1 | Polyacene derivatives and production thereof | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-1262469-A1 | POLYACENE DERIVATIVES AND PRODUCTION THEREOF | Japan Science and Technology Corporation (JP) | 2002-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030116755-A1 | Polyacene derivatives and production thereof | CBR1, HVCN1, H1-0 | LDHA 2792/4885LDHB 3121/4885PTPN1 3729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.