Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 2/20 | 0.33 |
| ▸ | RHOA | P61586 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979390 | 0.97 | SCN8A (0.38) | HTTSCN8APPARDCYP3A4KCNH2 | |
| SCHEMBL8629077 | 0.94 | SCN8A (0.40) | HTTSCN8ATP53GAAMAPK1 | |
| SCHEMBL8659999 | 0.93 | HTT (0.37) | HTTSCN8APPARDKDM4ECACNA1B | |
| SCHEMBL7979566 | 0.91 | SCN8A (0.43) | HTTSCN8APPARDCYP3A4KCNH2 | |
| SCHEMBL8408424 | 0.90 | HTT (0.38) | HTTSCN8ACACNA1BRHOCRHOA | |
| SCHEMBL7982119 | 0.89 | HTT (0.34) | HTTCACNA1BRHOCRHOASCN9A | |
| SCHEMBL8659923 | 0.89 | PPARD (0.40) | HTTTP53GAAPPARDCYP3A4 | |
| SCHEMBL7979320 | 0.89 | HTT (0.37) | HTTSCN8APPARDCACNA1BRHOC | |
| SCHEMBL7072956 | 0.88 | METAP1 (0.36) | TP53GAAPPARDKMT2APOLB | |
| SCHEMBL7976125 | 0.87 | RHOC (0.44) | PPARDRHOCRHOAMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214835-B1 | CONTROLLING INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0824514-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-02-25 | — | — | EP | disclosed |