Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 2/20 | 0.33 |
| ▸ | RHOA | P61586 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979566 | 0.97 | SCN8A (0.43) | SCN8AHTTPPARDCACNA1BPPARA | |
| SCHEMBL7976122 | 0.94 | HTT (0.36) | SCN8AHTTPPARDCACNA1BTP53 | |
| SCHEMBL7979320 | 0.92 | HTT (0.37) | SCN8AHTTPPARDCACNA1BPPARA | |
| SCHEMBL7979390 | 0.91 | SCN8A (0.38) | SCN8AHTTPPARDCACNA1BPPARA | |
| SCHEMBL7977675 | 0.89 | HTT (0.38) | SCN8AHTTPPARDCACNA1BPPARA | |
| SCHEMBL7977794 | 0.88 | HTT (0.37) | SCN8AHTTCACNA1BCYP3A4RHOC | |
| SCHEMBL8659999 | 0.88 | HTT (0.37) | SCN8AHTTPPARDCACNA1BRHOC | |
| SCHEMBL7976362 | 0.88 | HTT (0.41) | HTTTP53MAPK1CYP3A4KCNH2 | |
| SCHEMBL7975920 | 0.88 | HTT (0.40) | SCN8AHTTPPARDCACNA1BPPARA | |
| SCHEMBL7981953 | 0.86 | RHOC (0.44) | PPARDRHOCRHOAALDH1A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824514-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-02-25 | — | — | EP | disclosed |