SCHEMBL7976345

SCHEMBL7976345

ClC(Cl)=CCOc1cc(Cl)c(OCCCNc2cc(Cl)ccc2Cl)c(Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 2/20 0.35
HTT P42858 1/20 0.34
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ALPG P10696 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
CCR1 P32246 1/20 0.32
WDR5 P61964 1/20 0.32
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31
KDM4E B2RXH2 3/20 0.31
TP53 P04637 1/20 0.31
MAPK1 P28482 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7965903 0.88 TRPM5 (0.34) LMNAALDH1A1TDP1HTTMAPT
SCHEMBL7982287 0.86 HDAC1 (0.36) LMNAALDH1A1HTTMAPTSMN1; SMN2
SCHEMBL7977672 0.85 TDP1 (0.38) ALDH1A1TDP1HTTMAPTSMN1; SMN2
SCHEMBL8659785 0.81 PLAU (0.39) ALDH1A1HTTMAPTMEN1KMT2A
SCHEMBL7976346 0.80 KMT2A (0.48) ALDH1A1TDP1HTTMAPTMEN1
SCHEMBL7979272 0.80 HTT (0.38) LMNAALDH1A1HTTMAPTMEN1
SCHEMBL8408794 0.79 HTT (0.39) ALDH1A1HTTMAPTMEN1KMT2A
SCHEMBL8408754 0.79 HTT (0.39) ALDH1A1TDP1HTTMAPTMEN1
SCHEMBL7965715 0.79 KDM4E (0.41) LMNAALDH1A1TDP1HTTSMN1; SMN2
SCHEMBL8408726 0.79 HTT (0.42) ALDH1A1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed