Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | EIF4E | P06730 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976474 | 0.92 | PPARA (0.36) | KMT2AMEN1ALDH1A1PPARAPPARG | |
| SCHEMBL7524456 | 0.86 | PTGDR2 (0.38) | KMT2AMEN1ALDH1A1EIF4EPPARD | |
| SCHEMBL7976488 | 0.85 | MEN1 (0.33) | KMT2AMEN1ALDH1A1PPARAPPARG | |
| SCHEMBL7962801 | 0.84 | PPARA (0.35) | KMT2AMEN1PPARAPPARGEIF4E | |
| SCHEMBL7976487 | 0.79 | PPARA (0.37) | KMT2AMEN1ALDH1A1PPARAPPARG | |
| SCHEMBL7521850 | 0.77 | PPARA (0.37) | KMT2AALDH1A1PPARAPPARGNPC1 | |
| SCHEMBL7520084 | 0.77 | PTGIR (0.42) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7974229 | 0.76 | MAPT (0.38) | KMT2AMEN1ALDH1A1EIF4ERAB9A | |
| SCHEMBL7974227 | 0.76 | MAPT (0.38) | KMT2AMEN1ALDH1A1EIF4ERAB9A | |
| SCHEMBL7521207 | 0.76 | PTGIR (0.39) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |