Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974229 | 1.00 | MAPT (0.38) | MAPTHTTLMNANPSR1GAA | |
| SCHEMBL7523936 | 0.85 | MAPT (0.41) | MAPTHTTLMNANPSR1GAA | |
| SCHEMBL7523943 | 0.85 | MAPT (0.41) | MAPTHTTLMNANPSR1GAA | |
| SCHEMBL7976488 | 0.82 | MEN1 (0.33) | MAPTLMNANPSR1GAAKMT2A | |
| SCHEMBL7976487 | 0.81 | PPARA (0.37) | MAPTHTTLMNAKMT2AMEN1 | |
| SCHEMBL7521850 | 0.78 | PPARA (0.37) | MAPTLMNANPSR1GAAKMT2A | |
| SCHEMBL7962804 | 0.76 | KMT2A (0.34) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7974272 | 0.76 | PPARA (0.39) | MAPTLMNAKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL7976456 | 0.76 | PPARA (0.39) | MAPTLMNAKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL7972424 | 0.76 | PPARA (0.37) | MAPTLMNARAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |