SCHEMBL7976540

SCHEMBL7976540

CON1C(C)(C)CC(NCCCCCCNC2CC(C)(C)N(OC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.34
GNAI3 P08754 2/20 0.33
GNAO1 P09471 2/20 0.33
GNAI1 P63096 2/20 0.33
S1PR4 O95977 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10160218 0.93 GNAI3 (0.42) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL2369632 0.89 GNAI3 (0.34) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL12517417 0.84 GNAI3 (0.35) SLC2A1GNAI3GNAO1GNAI1S1PR4
SCHEMBL9429112 0.84
SCHEMBL15180169 0.84
SCHEMBL12267622 0.82 SMN1; SMN2 (0.30)
SCHEMBL893039 0.81 GNAI3 (0.37) SLC2A1GNAI3GNAO1GNAI1S1PR4
SCHEMBL18748179 0.80
SCHEMBL14467323 0.79
SCHEMBL295240 0.79 GNAI3 (0.35) SLC2A1GNAI3GNAO1GNAI1S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9963575-B2 Sterically hindered amine light stabilizers with a mixed functionalization BASF SE (DE) 2018-05-08 US disclosed
US-20170107352-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION BASF SE (DE) 2017-04-20 US disclosed
US-20170107352-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION BASF SE (DE) 2017-04-20 US disclosed
US-9550941-B2 Sterically hindered amine light stabilizers with a mixed functionalization BASF SE (DE) 2017-01-24 US disclosed
US-9550941-B2 Sterically hindered amine light stabilizers with a mixed functionalization BASF SE (DE) 2017-01-24 US disclosed
US-20130207043-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION BASF SE (DE) 2013-08-15 US disclosed
US-20130059952-A1 PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS BASF SE (DE) 2013-03-07 US disclosed
WO-2011086114-A1 PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS BASF SE (DE) 2011-07-21 WO disclosed
US-6265473-B1 STABILIZER; HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY CIBA SPECIALTY CHEMICALS CORP. 2001-07-24 US disclosed
WO-1998054174-A1 BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-12-03 WO disclosed
US-5714612-A LIGHT STABILIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-03 US disclosed
US-5506286-A BLENDING STABILZER WITH SYNTHETIC RESINS, RUBBERS, PAINTS, OILS TO STABILIZE FROM PHOTOOXIDATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-09 US disclosed
US-5384348-A Improved photostability for polymers, weather resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-24 US disclosed
EP-0389430-B1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA GEIGY AG (CH) 1994-10-26 EP disclosed
US-5021481-A For use with polymers CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed
EP-0389430-A1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130207043-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION C1S, H1-0, H1-2 SLC2A1 3903/4885GNAI3 2051/4885GNAO1 866/4885
US-20170107352-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION C1S, H1-0, H1-2 SLC2A1 4066/4885GNAI3 1931/4885GNAO1 740/4885
US-20130059952-A1 PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS PFAS, PHOSPHO1, PIK3CA SLC2A1 2602/4885GNAI3 2148/4885GNAO1 1873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.