Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467592 | 0.82 | PDGFRB (0.43) | ALDH1A1GAAGFERHSP90AB1EGFR | |
| SCHEMBL2439698 | 0.79 | GAA (0.42) | ALDH1A1GAAGFERHSP90AB1RORC | |
| SCHEMBL5084281 | 0.79 | HSP90AB1 (0.46) | ALDH1A1GAAGFERHSP90AB1EGFR | |
| SCHEMBL30633059 | 0.79 | HSP90AB1 (0.46) | ALDH1A1GAAGFERHSP90AB1EGFR | |
| SCHEMBL328578 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GAAGFERHSP90AB1EGFR | |
| SCHEMBL31463372 | 0.77 | CCR6 (0.46) | ALDH1A1GAAGFERHSP90AB1EGFR | |
| SCHEMBL13283682 | 0.77 | HSP90AB1 (0.55) | ALDH1A1GAAGFERHSP90AB1EGFR | |
| SCHEMBL10714231 | 0.76 | GAA (0.42) | ALDH1A1GAAGFERHSP90AB1KDM4E | |
| SCHEMBL7976613 | 0.76 | PDGFRB (0.51) | ALDH1A1GAAGFERHSP90AB1EGFR | |
| SCHEMBL23713473 | 0.75 | GAA (0.44) | ALDH1A1GAAGFERHSP90AB1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055138-A1 | AZOLE DERIVATIVES, THEIR PREPARATION AND USE | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |