Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735947 | 0.76 | GAA (0.55) | GAAKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6543615 | 0.72 | CYP26A1 (0.53) | CYP26A1CYP26B1GAAFFAR1LMNA | |
| SCHEMBL14677235 | 0.72 | CYP26A1 (0.50) | CYP26A1CYP26B1GAAFFAR1LMNA | |
| SCHEMBL14676451 | 0.71 | CYP26A1 (0.50) | CYP26A1CYP26B1GAAFFAR1LMNA | |
| SCHEMBL4927828 | 0.69 | CA12 (0.68) | GAAKDM4EALDH1A1PTGS1AKR1C3 | |
| SCHEMBL14677413 | 0.69 | CYP26A1 (0.43) | CYP26A1CYP26B1GAAFFAR1LMNA | |
| SCHEMBL14684905 | 0.68 | CYP26A1 (0.52) | CYP26A1CYP26B1GAAKDM4EBLM | |
| SCHEMBL7979172 | 0.68 | GAA (0.51) | CYP26A1CYP26B1GAAFFAR1LMNA | |
| SCHEMBL16422657 | 0.67 | CA12 (0.51) | FFAR1LMNAPIM1PIM2TP53 | |
| SCHEMBL7428695 | 0.67 | CYP26A1 (0.45) | CYP26A1CYP26B1GAAFFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001090105-A1 | ISOTHIAZOLES AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-11-29 | — | — | WO | disclosed |