Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPSE | Q9Y251 | 14/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976562 | 0.76 | CYP26A1 (0.46) | GAAHPSEKDM4EMEN1ALDH1A1 | |
| SCHEMBL11653626 | 0.76 | ELANE (0.48) | GAAKDM4EALDH1A1ELANE | |
| SCHEMBL5735345 | 0.75 | MAOA (0.53) | ELANE | |
| SCHEMBL7238282 | 0.74 | GAA (0.65) | GAAHPSEKDM4EMEN1ALDH1A1 | |
| SCHEMBL3807350 | 0.74 | GAA (0.69) | GAAHPSEKDM4EMEN1ALDH1A1 | |
| SCHEMBL11638474 | 0.72 | GAA (0.63) | GAAHPSEKDM4EMEN1ALDH1A1 | |
| SCHEMBL5733947 | 0.72 | GAA (0.75) | GAAHPSEKDM4EMEN1ALDH1A1 | |
| SCHEMBL3102305 | 0.71 | GAA (1.00) | GAAHPSEKDM4EMEN1ALDH1A1 | |
| SCHEMBL507169 | 0.70 | KDM4E (0.77) | GAAHPSEKDM4EALDH1A1 | |
| SCHEMBL7243392 | 0.70 | GAA (0.64) | GAAHPSEKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686128-A2 | Isothiazole derivatives and their use as pesticides | Syngenta Limited (GB) | 2006-08-02 | — | — | EP | disclosed |
| EP-1265892-B1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LTD (GB) | 2006-01-18 | — | — | EP | disclosed |
| US-20030207926-A1 | Isothiazole derivatives and their use as pesticides | SYNGENTA LIMITED (GB) | 2003-11-06 | — | — | US | disclosed |
| EP-1265892-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | Syngenta Limited (GB) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001055144-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207926-A1 | Isothiazole derivatives and their use as pesticides | CBR1, CBR3, CYP1B1 | GAA 4838/4885HPSE 4855/4885KDM4E 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.