Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.49 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11396835 | 0.88 | GAA (0.48) | GAACYP26A1CYP26B1ALDH1A1HPGD | |
| SCHEMBL12038075 | 0.82 | F2 (0.44) | FFAR1LMNATP53CA12CA2 | |
| SCHEMBL7997932 | 0.81 | CYP26A1 (0.48) | GAACYP26A1CYP26B1ALDH1A1HPGD | |
| SCHEMBL437855 | 0.79 | F2 (0.43) | ALDH1A1HPGDHSD17B10MAPTLMNA | |
| SCHEMBL6300465 | 0.79 | TBXAS1 (0.53) | TP53F2F10 | |
| SCHEMBL6543615 | 0.78 | CYP26A1 (0.53) | GAACYP26A1CYP26B1ALDH1A1HPGD | |
| SCHEMBL7428695 | 0.78 | CYP26A1 (0.45) | GAACYP26A1CYP26B1ALDH1A1HPGD | |
| SCHEMBL9268375 | 0.78 | F2 (0.43) | ALDH1A1HPGDKDM4EMAPTLMNA | |
| SCHEMBL5972981 | 0.76 | PPARG (0.47) | — | |
| SCHEMBL17592476 | 0.76 | PTGS1 (0.62) | GAAALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001090105-A1 | ISOTHIAZOLES AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-11-29 | — | — | WO | disclosed |