Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14034629 | 0.81 | AR (0.44) | HTR1ADRD2SLC6A2HTR2ASLC6A4 | |
| SCHEMBL5637889 | 0.81 | HTR1A (0.43) | HTR1ADRD2SLC6A2HTR2ASLC6A4 | |
| SCHEMBL30418049 | 0.80 | HPGD (0.40) | HTR1ADRD2SLC6A2HTR2ASLC6A4 | |
| SCHEMBL17277459 | 0.78 | TAAR1 (0.44) | TAAR1KIF11ALDH1A1MAPK1 | |
| SCHEMBL2799059 | 0.77 | ALDH1A1 (0.38) | TAAR1KIF11HTR1ADRD2SLC6A2 | |
| SCHEMBL10019247 | 0.77 | ALDH1A1 (0.38) | TAAR1KIF11HTR1ADRD2SLC6A2 | |
| SCHEMBL6610517 | 0.77 | HTR1A (0.40) | TAAR1KIF11HTR1ADRD2SLC6A2 | |
| SCHEMBL10019246 | 0.77 | MAPT (0.41) | HTR1ADRD2SLC6A2HTR2ASLC6A4 | |
| SCHEMBL4654113 | 0.76 | HTR1A (0.43) | TAAR1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL4027432 | 0.76 | ALDH1A1 (0.67) | HTR1ADRD2SLC6A2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064644-A1 | DICHLOROPYRIDYL- AND DICHLOROISOTHIAZOLYL-THIOCARBOXAMIDES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-09-07 | — | — | WO | disclosed |