Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976745 | 0.87 | ALDH1A1 (0.50) | ALOX5ALDH1A1MAPTPKMCHRM2 | |
| SCHEMBL18415480 | 0.85 | ALDH1A1 (0.51) | ALOX5ALDH1A1MAPTPKMCHRM2 | |
| SCHEMBL10061717 | 0.83 | MAPT (0.50) | ALOX5ALDH1A1MAPTPKMCHRM2 | |
| SCHEMBL10310214 | 0.81 | CHRM2 (0.47) | ALOX5ALDH1A1MAPTPKMCHRM2 | |
| SCHEMBL33528965 | 0.80 | ALDH1A1 (0.50) | ALOX5ALDH1A1MAPTPKMCHRM2 | |
| SCHEMBL27357988 | 0.80 | PKM (0.52) | ALOX5ALDH1A1MAPTPKMCHRM2 | |
| SCHEMBL20194513 | 0.79 | CHRM2 (0.49) | ALOX5ALDH1A1MAPTPKMCHRM2 | |
| SCHEMBL19712892 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTPKMCHRM2CYP2C19 | |
| SCHEMBL12017893 | 0.79 | PKM (0.47) | ALOX5ALDH1A1MAPTPKMCHRM2 | |
| SCHEMBL31396746 | 0.77 | EPHX2 (0.51) | ALDH1A1MAPTPKMCYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |