Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849200 | 1.00 | KDM4E (0.41) | KDM4ELMNAPOLBMAPTCA1 | |
| SCHEMBL1832624 | 0.83 | CTRB1 (0.33) | KDM4ELMNATSHR | |
| SCHEMBL9648206 | 0.83 | CTRB1 (0.33) | KDM4ELMNATSHR | |
| SCHEMBL10829859 | 0.83 | CTRB1 (0.33) | KDM4ELMNATSHR | |
| SCHEMBL10873133 | 0.81 | KDM4E (0.36) | KDM4ELMNAPOLBMAPTMTNR1A | |
| SCHEMBL4655182 | 0.81 | KDM4E (0.36) | KDM4ELMNAPOLBMAPTMTNR1A | |
| SCHEMBL28819066 | 0.77 | ALDH1A1 (0.42) | MTNR1AMTNR1B | |
| SCHEMBL22534064 | 0.77 | KDM4E (0.39) | KDM4ELMNARAB9A | |
| SCHEMBL6425835 | 0.77 | KDM4E (0.39) | KDM4ELMNARAB9A | |
| SCHEMBL1572438 | 0.77 | KDM4E (0.36) | KDM4ELMNAPOLBMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277583-B1 | COMBINING A MIXTURE OF PROTEINS COMPRISING THE TARGET PROTEIN WITH AN AFFINITY LABEL CONJUGATE COMPRISING AN OLIGOMER AND A BIOLOGICALLY ACTIVE COMPOUND AND HAS AN ACTIVATED FUNCTIONAL GROUP WHICH COVALENTLY BONDS TO THE TARGET PROTEIN | CONJUCHEM, INC. (CA) | 2001-08-21 | — | — | US | disclosed |
| EP-0885390-A1 | AFFINITY LABELING LIBRARIES AND APPLICATIONS THEREOF | Redcell Canada Inc. (CA) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997029372-A1 | AFFINITY LABELING LIBRARIES AND APPLICATIONS THEREOF | CONJUCHEM, INC. (CA) | 1997-08-14 | — | — | WO | disclosed |
| US-4870162-A | COUPLING WITH PROTEIN, ANTITUMOR | OMNICHEM (BE) | 1989-09-26 | — | — | US | disclosed |