Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.60 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.55 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679331 | 0.87 | NAAA (0.70) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL8690057 | 0.83 | NAAA (0.77) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL2736687 | 0.83 | NAAA (0.83) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL6359440 | 0.81 | NAAA (0.86) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL2639022 | 0.81 | NAAA (0.86) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL377246 | 0.81 | NAAA (0.79) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL12650953 | 0.80 | NAAA (0.62) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL19093034 | 0.80 | NAAA (0.62) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL2750425 | 0.79 | LMNA (0.41) | NAAAGNAI3GNAO1GNAI1KDM4E | |
| SCHEMBL9511929 | 0.79 | NAAA (0.83) | NAAAGNAI3GNAO1GNAI1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |