Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27273681 | 0.97 | L3MBTL1 (0.49) | L3MBTL1LMNAKMT2ANCEH1GAA | |
| SCHEMBL31053227 | 0.87 | LMNA (0.60) | L3MBTL1LMNAKMT2AGAAMEN1 | |
| SCHEMBL10979352 | 0.87 | LMNA (0.60) | L3MBTL1LMNAKMT2AGAAMEN1 | |
| SCHEMBL3993398 | 0.84 | LMNA (0.61) | L3MBTL1LMNAKMT2AGAAMEN1 | |
| SCHEMBL5118416 | 0.83 | L3MBTL1 (0.52) | L3MBTL1LMNAKMT2AGAAMEN1 | |
| SCHEMBL11158149 | 0.83 | LMNA (0.56) | L3MBTL1LMNAKMT2AGAAMEN1 | |
| SCHEMBL10916449 | 0.83 | L3MBTL1 (0.43) | L3MBTL1LMNAKMT2AGAAMEN1 | |
| SCHEMBL7821372 | 0.81 | TDP1 (0.57) | L3MBTL1LMNANCEH1GAATDP1 | |
| SCHEMBL31274977 | 0.80 | L3MBTL1 (0.52) | L3MBTL1LMNAKMT2AGAAMEN1 | |
| SCHEMBL10963427 | 0.79 | KMT2A (0.49) | L3MBTL1LMNAKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |
| EP-0971892-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Astra Pharmaceuticals Limited (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042670-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-10-01 | — | — | WO | disclosed |