Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977243 | 0.91 | MAPT (0.67) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL4727838 | 0.89 | MAPT (0.68) | MAPTMEN1KMT2ALMNAPTGER4 | |
| SCHEMBL31021118 | 0.89 | MAPT (0.68) | MAPTMEN1KMT2ALMNAPTGER4 | |
| SCHEMBL148001 | 0.79 | MAPT (0.85) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL29539965 | 0.79 | MAPT (0.85) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL29648254 | 0.78 | MAPT (0.67) | MAPTMEN1KMT2ALMNAPTGER4 | |
| SCHEMBL29794143 | 0.76 | PTGER4 (0.81) | MAPTMEN1KMT2ALMNAPTGER4 | |
| SCHEMBL4832600 | 0.76 | PTGER4 (0.81) | MAPTMEN1KMT2ALMNAPTGER4 | |
| SCHEMBL21076080 | 0.76 | RORC (0.52) | MAPTMEN1KMT2APTGER4RORC | |
| SCHEMBL11356589 | 0.76 | MAPT (0.62) | MAPTMEN1KMT2ALMNAPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |