Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976962 | 0.91 | MAPT (0.56) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL29539965 | 0.87 | MAPT (0.85) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL148001 | 0.87 | MAPT (0.85) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL21076080 | 0.84 | RORC (0.52) | MAPTMEN1KMT2ARORC | |
| SCHEMBL28710625 | 0.81 | MAPT (0.81) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL29767664 | 0.81 | MAPT (0.81) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL29666347 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL149167 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL16295058 | 0.79 | MAPT (0.72) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL16412008 | 0.78 | MAPT (0.67) | MAPTMEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |