Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827636 | 0.76 | POLB (0.42) | POLBALDH1A1TDP1KMT2AHTT | |
| SCHEMBL6928359 | 0.76 | POLB (0.42) | POLBALDH1A1TDP1KMT2AHTT | |
| SCHEMBL6946769 | 0.76 | POLB (0.42) | POLBALDH1A1TDP1KMT2AHTT | |
| SCHEMBL5716620 | 0.74 | HSD17B10 (0.30) | TDP1 | |
| SCHEMBL3674439 | 0.73 | MTNR1A (0.38) | ALDH1A1KMT2A | |
| SCHEMBL9781967 | 0.72 | — | — | |
| SCHEMBL5716496 | 0.70 | — | — | |
| SCHEMBL5401319 | 0.70 | MGAM (0.44) | ALDH1A1KMT2ATRPA1 | |
| SCHEMBL10916991 | 0.70 | CYP4F2 (0.44) | POLBALDH1A1HTTCYP2C19NPC1 | |
| SCHEMBL7625144 | 0.69 | KMT2A (0.42) | POLBALDH1A1KMT2AHTTGRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101623657-B | Catalyst systems and their use in metathesis reactions | LANXESS DEUTSCHLAND GMBH | 2013-11-06 | — | — | CN | claimed |
| CN-101623657-A | Catalyst systems and their use in metathesis reactions | LANXESS DEUTSCHLAND GMBH | 2010-01-13 | — | — | CN | claimed |
| CN-101366714-A | Acetylene derivatives having mGluR5 antagonistic activity | NOVARTIS AG (CH) | 2009-02-18 | — | — | CN | claimed |
| CN-1993128-A | N-substituted piperidines and their use as pharmaceuticals | INCYTE CORP (US) | 2007-07-04 | — | — | CN | claimed |
| US-6280900-B1 | RADIATION SENSITIVE COMPOSITION WITH ALKALINE DEVELOPER SOLUBLE IN POLYMER COATED ON SUBSTRATE | JSR CORPORATION (JP) | 2001-08-28 | — | — | US | claimed |
| CN-106661409-B | Priming paint for adhesive tape | 德莎欧洲股份公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-107418479-A | Pressure sensitive adhesive for bonding flexographic printing plates | 德莎欧洲股份公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-106661409-A | Primer for adhesive tapes | 德莎欧洲公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-104513137-B | A kind of 1,5-eneyne alcohol compound and synthetic method and application | SHAANXI NORMAL UNIVERSITY (CN) | 2016-05-04 | — | — | CN | disclosed |
| CN-101366714-B | Acetylene derivatives having mGluR5 antagonistic activity | NOVARTIS AG | 2014-09-17 | — | — | CN | disclosed |
| CN-101623657-B | Catalyst systems and their use in metathesis reactions | LANXESS DEUTSCHLAND GMBH | 2013-11-06 | — | — | CN | disclosed |
| CN-103212078-A | Combinations comprising mglur modulators for the treatment of parkinson's disease | NOVARTIS AG | 2013-07-24 | — | — | CN | disclosed |
| CN-101366714-A | Acetylene derivatives having mGluR5 antagonistic activity | NOVARTIS AG (CH) | 2009-02-18 | — | — | CN | disclosed |
| CN-100430059-C | Acetylene derivatives having mGluR5 antagonistic activity | NOVARTIS AG (CH) | 2008-11-05 | — | — | CN | disclosed |
| CN-101107745-A | Nonaqueous electrolyte solution and lithium secondary battery using same | UBE INDUSTRIES (JP) | 2008-01-16 | — | — | CN | disclosed |
| CN-1989647-A | Nonaqueous electrolytic solution and lithium secondary battery | UBE INDUSTRIES (JP) | 2007-06-27 | — | — | CN | disclosed |
| CN-1853307-A | Nonaqueous electrolytic solution for lithium secondary battery and lithium secondary battery using the same | UBE INDUSTRIES (JP) | 2006-10-25 | — | — | CN | disclosed |
| CN-1592623-A | Acetylene derivatives having mGluR5 antagonistic activity | NOVARTIS AG (CH) | 2005-03-09 | — | — | CN | disclosed |
| US-6280900-B1 | RADIATION SENSITIVE COMPOSITION WITH ALKALINE DEVELOPER SOLUBLE IN POLYMER COATED ON SUBSTRATE | JSR CORPORATION (JP) | 2001-08-28 | — | — | US | disclosed |
| CN-1039492-C | Herbicides | ZENECA LTD (GB) | 1998-08-12 | — | — | CN | disclosed |