SCHEMBL7977009

SCHEMBL7977009

O=C1C[C@H](Cc2ccccc2)CO1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 2/20 0.47
CHRM2 P08172 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
LTB4R Q15722 1/20 0.46
LTB4R2 Q9NPC1 1/20 0.46
MAOB P27338 1/20 0.45
HTR1A P08908 2/20 0.43
SIGMAR1 Q99720 2/20 0.43
CYP19A1 P11511 1/20 0.43
GBA1 P04062 1/20 0.43
TAAR1 Q96RJ0 2/20 0.41
CCR3 P51677 1/20 0.40
ABCB1 P08183 1/20 0.39
GRIN2B Q13224 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5859935 1.00 CHRM5 (0.47) CHRM5CHRM2CHRM4CHRM1CHRM3
SCHEMBL5236823 1.00 CHRM5 (0.47) CHRM5CHRM2CHRM4CHRM1CHRM3
SCHEMBL8772735 0.84 GBA1 (0.46) MAOBHTR1ASIGMAR1GBA1CCR3
SCHEMBL13215737 0.82 HTT (0.47) CHRM5CHRM2CHRM4CHRM1CHRM3
SCHEMBL5239977 0.82 TAAR1 (0.45) CHRM5CHRM2CHRM4CHRM1CHRM3
SCHEMBL2933979 0.82 GBA1 (0.44) MAOBHTR1ASIGMAR1CYP19A1GBA1
SCHEMBL6261865 0.81 GBA1 (0.46) SIGMAR1CYP19A1GBA1CCR3GRIN2B
SCHEMBL4701393 0.80 ALDH1A1 (0.45) CHRM5CHRM2CHRM4CHRM1CHRM3
SCHEMBL4392777 0.78 TAAR1 (0.48) TAAR1
SCHEMBL11310048 0.77 EED (0.50) LTB4RLTB4R2HTR1ACYP19A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960750-A Baeyer-Villiger monooxygenase, mutant and application thereof in preparation of chiral butyrolactone 华东理工大学 2023-04-14 CN disclosed
US-6274686-B1 RACEMIC MIXTURE OF ENANTIOMORPHS MOSBACH KLAUS (SE) 2001-08-14 US disclosed
EP-0988544-A2 AMIDE CONTAINING MOLECULAR IMPRINTED POLYMERS IGEN, INC. (US) 2000-03-29 EP disclosed
WO-1998054228-A2 AMIDE CONTAINING MOLECULAR IMPRINTED POLYMERS IGEN, INC. (US) 1998-12-03 WO disclosed