Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | BUB1 | O43683 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16397855 | 0.84 | TAAR1 (0.50) | TAAR1LMNAAKT1FKBP1ABUB1 | |
| SCHEMBL20439603 | 0.82 | GRM1 (0.37) | TAAR1FKBP1ANAAA | |
| SCHEMBL5859935 | 0.78 | CHRM5 (0.47) | TAAR1 | |
| SCHEMBL337537 | 0.78 | BUB1 (0.51) | TAAR1LMNAAKT1BUB1CTSL | |
| SCHEMBL5236823 | 0.78 | CHRM5 (0.47) | TAAR1 | |
| SCHEMBL7977009 | 0.78 | CHRM5 (0.47) | TAAR1 | |
| SCHEMBL665165 | 0.78 | LMNA (0.45) | TAAR1LMNAAKT1BUB1CTSL | |
| SCHEMBL1865729 | 0.76 | TSHR (0.52) | TAAR1LMNABUB1CTSLCTSB | |
| SCHEMBL27463829 | 0.76 | LMNA (0.52) | TAAR1LMNAAKT1CYP3A4TSHR | |
| SCHEMBL5239977 | 0.76 | TAAR1 (0.45) | TAAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307738-B1 | ARYL DIHYDRO-2H-BENZO[B][1,4]OXAZINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORY AND THE TREATMENT OF DISEASE | UNIV MICHIGAN REGENTS (US) | 2022-04-20 | — | — | EP | disclosed |
| US-9468706-B2 | Phosphoryl choline coating compositions | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-20150328375-A1 | Phosphoryl Choline Coating Compositions | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2015-11-19 | — | — | US | disclosed |
| EP-1732621-B1 | PHOSPHOLIPID AND NON-FOULING COATING COMPOSITIONS | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2009-12-09 | — | — | EP | disclosed |
| US-20050208093-A1 | Phosphoryl choline coating compositions | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050208093-A1 | Phosphoryl choline coating compositions | PHOSPHO1, CHKA, SGMS1 | TAAR1 1212/4885LMNA 961/4885AKT1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.