Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963446 | 0.82 | MAPT (0.57) | NPY5RMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL7979596 | 0.82 | NPY5R (0.52) | NPY5RMEN1KMT2AMAPTPOLB | |
| SCHEMBL7973597 | 0.79 | MAPT (0.44) | NPY5RMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL28266267 | 0.70 | NPY5R (0.59) | NPY5RMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL15458634 | 0.70 | MEN1 (0.58) | NPY5RMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL1594119 | 0.69 | NPY5R (0.72) | NPY5RMEN1KMT2AMAPTLMNA | |
| SCHEMBL150044 | 0.69 | BCHE (0.59) | NPY5RMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL29780042 | 0.69 | BCHE (0.59) | NPY5RMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL26237871 | 0.68 | MEN1 (0.59) | NPY5RMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL13301258 | 0.68 | MEN1 (0.49) | NPY5RMEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |