Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963446 | 0.86 | MAPT (0.57) | MAPTPOLBTSHRMAPK1HTT | |
| SCHEMBL7973746 | 0.82 | NPY5R (0.44) | MAPTPOLBMAPK1NPY5RPTGES | |
| SCHEMBL7977151 | 0.79 | NPY5R (0.49) | MAPTPOLBTSHRMAPK1HTT | |
| SCHEMBL7974767 | 0.77 | NPY5R (0.54) | MAPTPOLBTSHRMAPK1HTT | |
| SCHEMBL23148499 | 0.71 | CYP1A2 (0.56) | RORARORCRORBKDM4ECYP1A2 | |
| SCHEMBL7976798 | 0.70 | RORC (0.52) | MAPTPOLBTSHRMAPK1HTT | |
| SCHEMBL7979488 | 0.69 | NPSR1 (0.56) | MAPTPOLBMAPK1NPY5RNPSR1 | |
| SCHEMBL7977223 | 0.69 | NPY5R (0.53) | MAPTPOLBTSHRMAPK1HTT | |
| SCHEMBL23318288 | 0.68 | KMT2A (0.44) | MAPTPOLBMAPK1HTTL3MBTL1 | |
| SCHEMBL13049599 | 0.68 | NPY5R (0.41) | MAPTMAPK1HTTNPY5RRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |