Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973597 | 0.86 | MAPT (0.44) | MAPTMAPK1HTTL3MBTL1POLB | |
| SCHEMBL7976798 | 0.83 | RORC (0.52) | MAPTMAPK1HTTL3MBTL1POLB | |
| SCHEMBL7974767 | 0.83 | NPY5R (0.54) | MAPTMAPK1HTTL3MBTL1POLB | |
| SCHEMBL7977151 | 0.82 | NPY5R (0.49) | MAPTMAPK1HTTL3MBTL1POLB | |
| SCHEMBL25179738 | 0.82 | NPSR1 (0.68) | MAPTMAPK1HTTL3MBTL1POLB | |
| SCHEMBL7979488 | 0.82 | NPSR1 (0.56) | MAPTMAPK1POLBNPSR1MEN1 | |
| SCHEMBL7977223 | 0.82 | NPY5R (0.53) | MAPTMAPK1HTTL3MBTL1POLB | |
| SCHEMBL29920588 | 0.80 | MAPT (0.57) | MAPTMAPK1HTTL3MBTL1POLB | |
| SCHEMBL20945450 | 0.80 | MAPT (0.57) | MAPTMAPK1HTTL3MBTL1POLB | |
| SCHEMBL2287907 | 0.78 | NPSR1 (0.63) | MAPTMAPK1HTTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |