Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381005 | 0.82 | SMN1; SMN2 (0.42) | KMT2AMAPTNPC1RAB9A | |
| SCHEMBL4381409 | 0.80 | CHRNB2 (0.52) | ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL7961200 | 0.77 | EPHX2 (0.52) | KMT2AALDH1A1HTTMEN1MAPT | |
| SCHEMBL9038302 | 0.75 | TP53 (0.51) | KMT2AAGTR1ALDH1A1HTTMEN1 | |
| SCHEMBL8120852 | 0.75 | ALDH1A1 (0.39) | KMT2AALDH1A1HTTMEN1MAPT | |
| SCHEMBL7974153 | 0.74 | CHRNB2 (0.53) | KMT2AALDH1A1MEN1MAPTHPGD | |
| SCHEMBL5016737 | 0.72 | ALDH1A1 (0.58) | KMT2AAGTR1ALDH1A1HTTMEN1 | |
| SCHEMBL4383633 | 0.71 | KMT2A (0.45) | KMT2A | |
| Hydrochloric Acid SCHEMBL9459758 | 0.70 | CYP4F2 (0.37) | AGTR1 | |
| SCHEMBL27581016 | 0.70 | KMT2A (0.58) | KMT2AAGTR1ALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |